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p53 induces transcriptional and translational programs to suppress cell proliferation and growth
BACKGROUND: Cell growth and proliferation are tightly connected to ensure that appropriately sized daughter cells are generated following mitosis. Energy stress blocks cell growth and proliferation, a critical response for survival under extreme conditions. Excessive oncogenic stress leads to p53 ac...
Autores principales: | Loayza-Puch, Fabricio, Drost, Jarno, Rooijers, Koos, Lopes, Rui, Elkon, Ran, Agami, Reuven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053767/ https://www.ncbi.nlm.nih.gov/pubmed/23594524 http://dx.doi.org/10.1186/gb-2013-14-4-r32 |
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