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Genome-wide co-localization of Polycomb orthologs and their effects on gene expression in human fibroblasts

BACKGROUND: Polycomb group proteins form multicomponent complexes that are important for establishing lineage-specific patterns of gene expression. Mammalian cells encode multiple permutations of the prototypic Polycomb repressive complex 1 (PRC1) with little evidence for functional specialization....

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Detalles Bibliográficos
Autores principales: Pemberton, Helen, Anderton, Emma, Patel, Harshil, Brookes, Sharon, Chandler, Hollie, Palermo, Richard, Stock, Julie, Rodriguez-Niedenführ, Marc, Racek, Tomas, de Breed, Lucas, Stewart, Aengus, Matthews, Nik, Peters, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053772/
https://www.ncbi.nlm.nih.gov/pubmed/24485159
http://dx.doi.org/10.1186/gb-2014-15-2-r23