The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells

BACKGROUND: Pluripotency is characterized by a unique transcriptional state, in which lineage-specification genes are poised for transcription upon exposure to appropriate stimuli, via a bivalency mechanism involving the simultaneous presence of activating and repressive methylation marks at promote...

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Detalles Bibliográficos
Autores principales: Castelo-Branco, Gonçalo, Amaral, Paulo P, Engström, Pär G, Robson, Samuel C, Marques, Sueli C, Bertone, Paul, Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053805/
https://www.ncbi.nlm.nih.gov/pubmed/24044525
http://dx.doi.org/10.1186/gb-2013-14-9-r98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053805/
https://www.ncbi.nlm.nih.gov/pubmed/24044525
http://dx.doi.org/10.1186/gb-2013-14-9-r98

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