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The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells
BACKGROUND: Pluripotency is characterized by a unique transcriptional state, in which lineage-specification genes are poised for transcription upon exposure to appropriate stimuli, via a bivalency mechanism involving the simultaneous presence of activating and repressive methylation marks at promote...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053805/ https://www.ncbi.nlm.nih.gov/pubmed/24044525 http://dx.doi.org/10.1186/gb-2013-14-9-r98 |