Characterizing and measuring bias in sequence data

BACKGROUND: DNA sequencing technologies deviate from the ideal uniform distribution of reads. These biases impair scientific and medical applications. Accordingly, we have developed computational methods for discovering, describing and measuring bias. RESULTS: We applied these methods to the Illumin...

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Detalles Bibliográficos
Autores principales: Ross, Michael G, Russ, Carsten, Costello, Maura, Hollinger, Andrew, Lennon, Niall J, Hegarty, Ryan, Nusbaum, Chad, Jaffe, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053816/
https://www.ncbi.nlm.nih.gov/pubmed/23718773
http://dx.doi.org/10.1186/gb-2013-14-5-r51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053816/
https://www.ncbi.nlm.nih.gov/pubmed/23718773
http://dx.doi.org/10.1186/gb-2013-14-5-r51

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