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Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies

Expression quantitative trait loci (eQTL) mapping is a tool that can systematically identify genetic variation affecting gene expression. eQTL mapping studies have shown that certain genomic locations, referred to as regulatory hotspots, may affect the expression levels of many genes. Recently, stud...

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Detalles Bibliográficos
Autores principales: J Joo, Jong Wha, Sul, Jae Hoon, Han, Buhm, Ye, Chun, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053820/
https://www.ncbi.nlm.nih.gov/pubmed/24708878
http://dx.doi.org/10.1186/gb-2014-15-4-r61