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Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein

BACKGROUND: Smaug is an RNA-binding protein that induces the degradation and represses the translation of mRNAs in the early Drosophila embryo. Smaug has two identified direct target mRNAs that it differentially regulates: nanos and Hsp83. Smaug represses the translation of nanos mRNA but has only a...

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Detalles Bibliográficos
Autores principales: Chen, Linan, Dumelie, Jason G, Li, Xiao, Cheng, Matthew HK, Yang, Zhiyong, Laver, John D, Siddiqui, Najeeb U, Westwood, J Timothy, Morris, Quaid, Lipshitz, Howard D, Smibert, Craig A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053848/
https://www.ncbi.nlm.nih.gov/pubmed/24393533
http://dx.doi.org/10.1186/gb-2014-15-1-r4