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Inactive or moderately active human promoters are enriched for inter-individual epialleles

BACKGROUND: Inter-individual epigenetic variation, due to genetic, environmental or random influences, is observed in many eukaryotic species. In mammals, however, the molecular nature of epiallelic variation has been poorly defined, partly due to the restricted focus on DNA methylation. Here we rep...

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Detalles Bibliográficos
Autores principales: Gemma, Carolina, Ramagopalan, Sreeram V, Down, Thomas A, Beyan, Huriya, Hawa, Mohammed I, Holland, Michelle L, Hurd, Paul J, Giovannoni, Gavin, David Leslie, R, Ebers, George C, Rakyan, Vardhman K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053860/
https://www.ncbi.nlm.nih.gov/pubmed/23706135
http://dx.doi.org/10.1186/gb-2013-14-5-r43