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CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes

BACKGROUND: Bacteria and archaea develop immunity against invading genomes by incorporating pieces of the invaders' sequences, called spacers, into a clustered regularly interspaced short palindromic repeats (CRISPR) locus between repeats, forming arrays of repeat-spacer units. When spacers are...

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Detalles Bibliográficos
Autores principales: Zhang, Quan, Rho, Mina, Tang, Haixu, Doak, Thomas G, Ye, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053933/
https://www.ncbi.nlm.nih.gov/pubmed/23628424
http://dx.doi.org/10.1186/gb-2013-14-4-r40