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CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes
BACKGROUND: Bacteria and archaea develop immunity against invading genomes by incorporating pieces of the invaders' sequences, called spacers, into a clustered regularly interspaced short palindromic repeats (CRISPR) locus between repeats, forming arrays of repeat-spacer units. When spacers are...
Autores principales: | Zhang, Quan, Rho, Mina, Tang, Haixu, Doak, Thomas G, Ye, Yuzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053933/ https://www.ncbi.nlm.nih.gov/pubmed/23628424 http://dx.doi.org/10.1186/gb-2013-14-4-r40 |
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