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Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies
In this brief review, we discuss immune tolerance as a factor that determines the magnitude and quality of serum antibody responses to HIV-1 infection and vaccination in the context of recent work. We propose that many conserved, neutralizing epitopes of HIV-1 are weakly immunogenic because they mim...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053940/ https://www.ncbi.nlm.nih.gov/pubmed/24932410 http://dx.doi.org/10.3390/vaccines2010001 |