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The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
BACKGROUND: DNA methylation plays an essential role in the regulation of gene expression. While its presence near the transcription start site of a gene has been associated with reduced expression, the variation in methylation levels across individuals, its environmental or genetic causes, and its a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053980/ https://www.ncbi.nlm.nih.gov/pubmed/24555846 http://dx.doi.org/10.1186/gb-2014-15-2-r37 |