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DNA binding specificities of the long zinc-finger recombination protein PRDM9

BACKGROUND: Meiotic recombination ensures proper segregation of homologous chromosomes and creates genetic variation. In many organisms, recombination occurs at limited sites, termed 'hotspots', whose positions in mammals are determined by PR domain member 9 (PRDM9), a long-array zinc-fing...

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Detalles Bibliográficos
Autores principales: Billings, Timothy, Parvanov, Emil D, Baker, Christopher L, Walker, Michael, Paigen, Kenneth, Petkov, Petko M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053984/
https://www.ncbi.nlm.nih.gov/pubmed/23618393
http://dx.doi.org/10.1186/gb-2013-14-4-r35