Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

BACKGROUND: DNA methylation is an epigenetic modification that changes with age in human tissues, although the mechanisms and specificity of this process are still poorly understood. We compared CpG methylation changes with age across 283 human blood, brain, kidney, and skeletal muscle samples using...

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Detalles Bibliográficos
Autores principales: Day, Kenneth, Waite, Lindsay L, Thalacker-Mercer, Anna, West, Andrew, Bamman, Marcas M, Brooks, James D, Myers, Richard M, Absher, Devin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053985/
https://www.ncbi.nlm.nih.gov/pubmed/24034465
http://dx.doi.org/10.1186/gb-2013-14-9-r102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053985/
https://www.ncbi.nlm.nih.gov/pubmed/24034465
http://dx.doi.org/10.1186/gb-2013-14-9-r102

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