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Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

BACKGROUND: Human breast cancer is a heterogeneous disease consisting of multiple molecular subtypes. Genetically engineered mouse models are a useful resource for studying mammary cancers in vivo under genetically controlled and immune competent conditions. Identifying murine models with conserved...

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Detalles Bibliográficos
Autores principales: Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Harrell, Joshua Chuck, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053990/
https://www.ncbi.nlm.nih.gov/pubmed/24220145
http://dx.doi.org/10.1186/gb-2013-14-11-r125