Cargando…
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
BACKGROUND: Human breast cancer is a heterogeneous disease consisting of multiple molecular subtypes. Genetically engineered mouse models are a useful resource for studying mammary cancers in vivo under genetically controlled and immune competent conditions. Identifying murine models with conserved...
Autores principales: | Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Harrell, Joshua Chuck, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053990/ https://www.ncbi.nlm.nih.gov/pubmed/24220145 http://dx.doi.org/10.1186/gb-2013-14-11-r125 |
Ejemplares similares
-
Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy
por: Pfefferle, Adam D., et al.
Publicado: (2015) -
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers
por: Pfefferle, Adam D., et al.
Publicado: (2016) -
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
por: Prat, Aleix, et al.
Publicado: (2010) -
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor
por: Pfefferle, Adam D., et al.
Publicado: (2019) -
The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas
por: Herschkowitz, Jason I, et al.
Publicado: (2008)