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Integrated analysis of recurrent properties of cancer genes to identify novel drivers

The heterogeneity of cancer genomes in terms of acquired mutations complicates the identification of genes whose modification may exert a driver role in tumorigenesis. In this study, we present a novel method that integrates expression profiles, mutation effects, and systemic properties of mutated g...

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Detalles Bibliográficos
Autores principales: D'Antonio, Matteo, Ciccarelli, Francesca D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054099/
https://www.ncbi.nlm.nih.gov/pubmed/23718799
http://dx.doi.org/10.1186/gb-2013-14-5-r52