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Implications of Differential Age Distribution of Disease-Associated Meningococcal Lineages for Vaccine Development

New vaccines targeting meningococci expressing serogroup B polysaccharide have been developed, with some being licensed in Europe. Coverage depends on the distribution of disease-associated genotypes, which may vary by age. It is well established that a small number of hyperinvasive lineages account...

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Detalles Bibliográficos
Autores principales: Brehony, Carina, Trotter, Caroline L., Ramsay, Mary E., Chandra, Manosree, Jolley, Keith A., van der Ende, Arie, Carion, Françoise, Berthelsen, Lene, Hoffmann, Steen, Harðardóttir, Hjördís, Vazquez, Julio A., Murphy, Karen, Toropainen, Maija, Caniça, Manuela, Ferreira, Eugenia, Diggle, Mathew, Edwards, Giles F., Taha, Muhamed-Kheir, Stefanelli, Paola, Kriz, Paula, Gray, Steve J., Fox, Andrew J., Jacobsson, Susanne, Claus, Heike, Vogel, Ulrich, Tzanakaki, Georgina, Heuberger, Sigrid, Caugant, Dominique A., Frosch, Matthias, Maiden, Martin C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054250/
https://www.ncbi.nlm.nih.gov/pubmed/24695776
http://dx.doi.org/10.1128/CVI.00133-14