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Effect of combined treatment with clozapine and metformin on fasting blood glucose, insulin level, and expression of the glucose transporter-2 (GLUT(2)) in Sprague-Dawley rats

BACKGROUND: Antipsychotic medications can cause an increase in blood glucose and the development of type II diabetes. Metformin may ameliorate these side effects. OBJECTIVE: Assess whether or not metformin reduces the abnormalities in glucose metabolism that occur with use of the antipsychotic cloza...

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Detalles Bibliográficos
Autores principales: Gao, Lan, Wang, Gaohua, Liu, Hao, Yan, Chaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of the Shanghai Archives of Psychiatry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054550/
https://www.ncbi.nlm.nih.gov/pubmed/24991150
http://dx.doi.org/10.3969/j.issn.1002-0829.2013.03.004