Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice

INTRODUCTION: The low-density lipoprotein receptor-related protein (LRP1) and its family members have been implicated in the pathogenesis of Alzheimer's disease. Multiple susceptibility factors converge to metabolic pathways that involve LRP1, including modulation of the processing of amyloid p...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Guilian, Green, Cameron C, Fromholt, Susan E, Borchelt, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054673/
https://www.ncbi.nlm.nih.gov/pubmed/22537779
http://dx.doi.org/10.1186/alzrt110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054673/
https://www.ncbi.nlm.nih.gov/pubmed/22537779
http://dx.doi.org/10.1186/alzrt110

Ejemplares similares