Virmid: accurate detection of somatic mutations with sample impurity inference

Detection of somatic variation using sequence from disease-control matched data sets is a critical first step. In many cases including cancer, however, it is hard to isolate pure disease tissue, and the impurity hinders accurate mutation analysis by disrupting overall allele frequencies. Here, we pr...

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Detalles Bibliográficos
Autores principales: Kim, Sangwoo, Jeong, Kyowon, Bhutani, Kunal, Lee, Jeong Ho, Patel, Anand, Scott, Eric, Nam, Hojung, Lee, Hayan, Gleeson, Joseph G, Bafna, Vineet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054681/
https://www.ncbi.nlm.nih.gov/pubmed/23987214
http://dx.doi.org/10.1186/gb-2013-14-8-r90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054681/
https://www.ncbi.nlm.nih.gov/pubmed/23987214
http://dx.doi.org/10.1186/gb-2013-14-8-r90

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