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SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum

TANGO1 binds and exports Procollagen VII from the endoplasmic reticulum (ER). In this study, we report a connection between the cytoplasmic domain of TANGO1 and SLY1, a protein that is required for membrane fusion. Knockdown of SLY1 by siRNA arrested Procollagen VII in the ER without affecting the r...

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Detalles Bibliográficos
Autores principales: Nogueira, Cristina, Erlmann, Patrik, Villeneuve, Julien, Santos, António JM, Martínez-Alonso, Emma, Martínez-Menárguez, José Ángel, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054776/
https://www.ncbi.nlm.nih.gov/pubmed/24842878
http://dx.doi.org/10.7554/eLife.02784