Sunitinib Combined with Angiotensin-2 Type-1 Receptor Antagonists Induces More Necrosis: A Murine Xenograft Model of Renal Cell Carcinoma

Background. Angiotensin-2 type-1 receptor antagonists not are only antihypertensive drugs but also can inhibit VEGF production. We hypothesised that adding telmisartan to sunitinib could potentiate the antiangiogenic effects. Material and Methods. 786-O cell lines were injected in nude mice. After t...

Descripción completa

Detalles Bibliográficos
Autores principales: Verhoest, Grégory, Dolley-Hitze, Thibault, Jouan, Florence, Belaud-Rotureau, Marc-Antoine, Oger, Emmanuel, Lavenu, Audrey, Bensalah, Karim, Arlot-Bonnemains, Yannick, Collet, Nicolas, Rioux-Leclercq, Nathalie, Vigneau, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054801/
https://www.ncbi.nlm.nih.gov/pubmed/24967411
http://dx.doi.org/10.1155/2014/901371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054801/
https://www.ncbi.nlm.nih.gov/pubmed/24967411
http://dx.doi.org/10.1155/2014/901371

Ejemplares similares