A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

BACKGROUND: Large-scale annotation efforts have improved our ability to coarsely predict regulatory elements throughout vertebrate genomes. However, it is unclear how complex spatiotemporal patterns of gene expression driven by these elements emerge from the activity of short, transcription factor b...

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Detalles Bibliográficos
Autores principales: Smith, Robin P, Riesenfeld, Samantha J, Holloway, Alisha K, Li, Qiang, Murphy, Karl K, Feliciano, Natalie M, Orecchia, Lorenzo, Oksenberg, Nir, Pollard, Katherine S, Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054837/
https://www.ncbi.nlm.nih.gov/pubmed/23867016
http://dx.doi.org/10.1186/gb-2013-14-7-r72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054837/
https://www.ncbi.nlm.nih.gov/pubmed/23867016
http://dx.doi.org/10.1186/gb-2013-14-7-r72

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