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Sequential Acquisition of T Cells and Antibodies to Nontyphoidal Salmonella in Malawian Children

Background. Salmonella Typhimurium (STm) remain a prominent cause of bacteremia in sub-Saharan Africa. Complement-fixing antibodies to STm develop by 2 years of age. We hypothesized that STm-specific CD4(+) T cells develop alongside this process. Methods. Eighty healthy Malawian children aged 0–60 m...

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Detalles Bibliográficos
Autores principales: Nyirenda, Tonney S., Gilchrist, James J., Feasey, Nicholas A., Glennie, Sarah J., Bar-Zeev, Naor, Gordon, Melita A., MacLennan, Calman A., Mandala, Wilson L., Heyderman, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054899/
https://www.ncbi.nlm.nih.gov/pubmed/24443544
http://dx.doi.org/10.1093/infdis/jiu045