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Polyol Pathway Exacerbated Ischemia/Reperfusion-Induced Injury in Steatotic Liver

Background. The polyol pathway, a bypass pathway of glucose metabolism initiated by aldose reductase (AR), has been shown to play an important role in mediating tissue ischemia/reperfusion (I/R) impairment recently. Here, we investigated how and why this pathway might affect the fatty liver followin...

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Detalles Bibliográficos
Autores principales: Zhang, Changhe, Huang, Changjun, Tian, Yuan, Li, Xiangcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055005/
https://www.ncbi.nlm.nih.gov/pubmed/24967007
http://dx.doi.org/10.1155/2014/963629