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Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators

INTRODUCTION: Transplanting mesenchymal stromal cells (MSCs) or their derivatives into a neurodegenerative environment is believed to be beneficial because of the trophic support, migratory guidance, immunosuppression, and neurogenic stimuli they provide. SB623, a cell therapy for the treatment of c...

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Detalles Bibliográficos
Autores principales: Aizman, Irina, Tirumalashetty, Brenna J, McGrogan, Michael, Case, Casey C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055059/
https://www.ncbi.nlm.nih.gov/pubmed/24572070
http://dx.doi.org/10.1186/scrt418