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The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional

INTRODUCTION: We previously demonstrated that the lifespan of primary human keratinocytes could be extended indefinitely by culture in the presence of the Rho kinase (ROCK) inhibitor Y-27632. This technique has proven to be very useful in diverse areas of basic and clinical research. METHODS: In thi...

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Detalles Bibliográficos
Autores principales: Chapman, Sandra, McDermott, David H, Shen, Kui, Jang, Moon Kyoo, McBride, Alison A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055106/
https://www.ncbi.nlm.nih.gov/pubmed/24774536
http://dx.doi.org/10.1186/scrt449