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Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated signalling pathways

INTRODUCTION: Fibronectin (FN) is commonly used in the development of serum-free media for the expansion of mesenchymal stem cells (MSCs). This study was aimed to observe if thrombin could stimulate FN secretion by human bone marrow MSCs and investigate the potential underlying mechanisms. METHODS:...

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Detalles Bibliográficos
Autores principales: Chen, Jin, Ma, Yujie, Wang, Zi, Wang, Hengxiang, Wang, Lisheng, Xiao, Fengjun, Wang, Hua, Tan, Jianming, Guo, Zikuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055141/
https://www.ncbi.nlm.nih.gov/pubmed/24636778
http://dx.doi.org/10.1186/scrt424