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Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated signalling pathways
INTRODUCTION: Fibronectin (FN) is commonly used in the development of serum-free media for the expansion of mesenchymal stem cells (MSCs). This study was aimed to observe if thrombin could stimulate FN secretion by human bone marrow MSCs and investigate the potential underlying mechanisms. METHODS:...
Autores principales: | Chen, Jin, Ma, Yujie, Wang, Zi, Wang, Hengxiang, Wang, Lisheng, Xiao, Fengjun, Wang, Hua, Tan, Jianming, Guo, Zikuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055141/ https://www.ncbi.nlm.nih.gov/pubmed/24636778 http://dx.doi.org/10.1186/scrt424 |
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