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Mesenchymal stem cells with overexpression of midkine enhance cell survival and attenuate cardiac dysfunction in a rat model of myocardial infarction

INTRODUCTION: Elevated midkine (MK) expression may contribute to ventricular remodeling and ameliorate cardiac dysfunction after myocardial infarction (MI). Ex vivo modification of signaling mechanisms in mesenchymal stem cells (MSCs) with MK overexpression may improve the efficacy of cell-based the...

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Detalles Bibliográficos
Autores principales: Zhao, Shu-Li, Zhang, Yao-Jun, Li, Ming-Hui, Zhang, Xin-Lei, Chen, Shao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055147/
https://www.ncbi.nlm.nih.gov/pubmed/24635859
http://dx.doi.org/10.1186/scrt425