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Mesenchymal stem cells with overexpression of midkine enhance cell survival and attenuate cardiac dysfunction in a rat model of myocardial infarction
INTRODUCTION: Elevated midkine (MK) expression may contribute to ventricular remodeling and ameliorate cardiac dysfunction after myocardial infarction (MI). Ex vivo modification of signaling mechanisms in mesenchymal stem cells (MSCs) with MK overexpression may improve the efficacy of cell-based the...
Autores principales: | Zhao, Shu-Li, Zhang, Yao-Jun, Li, Ming-Hui, Zhang, Xin-Lei, Chen, Shao-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055147/ https://www.ncbi.nlm.nih.gov/pubmed/24635859 http://dx.doi.org/10.1186/scrt425 |
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