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Application of Molecular Modeling to Urokinase Inhibitors Development

Urokinase-type plasminogen activator (uPA) plays an important role in the regulation of diverse physiologic and pathologic processes. Experimental research has shown that elevated uPA expression is associated with cancer progression, metastasis, and shortened survival in patients, whereas suppressio...

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Detalles Bibliográficos
Autores principales: Sulimov, V. B., Katkova, E. V., Oferkin, I. V., Sulimov, A. V., Romanov, A. N., Roschin, A. I., Beloglazova, I. B., Plekhanova, O. S., Tkachuk, V. A., Sadovnichiy, V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055159/
https://www.ncbi.nlm.nih.gov/pubmed/24967388
http://dx.doi.org/10.1155/2014/625176