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Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli

BACKGROUND: Trans-4-hydroxy-L-proline (trans-Hyp), one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. Although there are some natural biosynthetic pathways of trans-Hyp existing in microorganisms, the yield is still too low to be sca...

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Detalles Bibliográficos
Autores principales: Yi, Yulan, Sheng, Huakai, Li, Zhimin, Ye, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055215/
https://www.ncbi.nlm.nih.gov/pubmed/24885047
http://dx.doi.org/10.1186/1472-6750-14-44