Auto-induction of phase I and phase II metabolism of artemisinin in healthy Chinese subjects after oral administration of a new artemisinin-piperaquine fixed combination

BACKGROUND: Artequick is a relatively inexpensive artemisinin (Qing-hao-su; QHS)-based combination therapy (ACT) that contains QHS and piperaquine (PQ), which has not been widely used because of the decreased concentration level of QHS after repeated oral administrations for five to seven days as a...

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Detalles Bibliográficos
Autores principales: Zang, Meitong, Zhu, Fanping, Li, Xinxiu, Yang, Aijuan, Xing, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055232/
https://www.ncbi.nlm.nih.gov/pubmed/24889062
http://dx.doi.org/10.1186/1475-2875-13-214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055232/
https://www.ncbi.nlm.nih.gov/pubmed/24889062
http://dx.doi.org/10.1186/1475-2875-13-214

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