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Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function

Glutamylation is a functionally important tubulin posttranslational modification enriched on stable microtubules of neuronal axons, mitotic spindles, centrioles, and cilia. In vertebrates, balanced activities of tubulin glutamyl ligase and cytoplasmic carboxypeptidase deglutamylase enzymes maintain...

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Detalles Bibliográficos
Autores principales: Pathak, Narendra, Austin-Tse, Christina A., Liu, Yan, Vasilyev, Aleksandr, Drummond, Iain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055263/
https://www.ncbi.nlm.nih.gov/pubmed/24743595
http://dx.doi.org/10.1091/mbc.E13-01-0033