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The adaptor protein GULP promotes Jedi-1–mediated phagocytosis through a clathrin-dependent mechanism

During the development of the peripheral nervous system, the large number of apoptotic neurons generated are phagocytosed by glial precursor cells. This clearance is mediated, in part, through the mammalian engulfment receptor Jedi-1. However, the mechanisms by which Jedi-1 mediates phagocytosis are...

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Detalles Bibliográficos
Autores principales: Sullivan, Chelsea S., Scheib, Jami L., Ma, Zhong, Dang, Rajan P., Schafer, Johanna M., Hickman, Francis E., Brodsky, Frances M., Ravichandran, Kodi S., Carter, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055271/
https://www.ncbi.nlm.nih.gov/pubmed/24743597
http://dx.doi.org/10.1091/mbc.E13-11-0658