The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity

BACKGROUND: Photoimmunotherapy (PIT) is a highly cell-selective cancer therapy, which employs monoclonal antibodies conjugated to a potent photosensitizer (mAb-IR700). Once the conjugate has bound to the target cell, exposure to near infrared (NIR) light induces necrosis only in targeted cells with...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakajima, Takahito, Sato, Kazuhide, Hanaoka, Hirofumi, Watanabe, Rira, Harada, Toshiko, Choyke, Peter L, Kobayashi, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055275/
https://www.ncbi.nlm.nih.gov/pubmed/24885589
http://dx.doi.org/10.1186/1471-2407-14-389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055275/
https://www.ncbi.nlm.nih.gov/pubmed/24885589
http://dx.doi.org/10.1186/1471-2407-14-389

Ejemplares similares