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Comparative Analysis of Human Tissue Interactomes Reveals Factors Leading to Tissue-Specific Manifestation of Hereditary Diseases

An open question in human genetics is what underlies the tissue-specific manifestation of hereditary diseases, which are caused by genomic aberrations that are present in cells across the human body. Here we analyzed this phenomenon for over 300 hereditary diseases by using comparative network analy...

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Detalles Bibliográficos
Autores principales: Barshir, Ruth, Shwartz, Omer, Smoly, Ilan Y., Yeger-Lotem, Esti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055280/
https://www.ncbi.nlm.nih.gov/pubmed/24921629
http://dx.doi.org/10.1371/journal.pcbi.1003632