Prediction of Methotrexate Clinical Response in Portuguese Rheumatoid Arthritis Patients: Implication of MTHFR rs1801133 and ATIC rs4673993 Polymorphisms

Objective. Methotrexate (MTX), the most used drug in rheumatoid arthritis (RA) treatment, showing variability in clinical response, is often associated with genetic polymorphisms. This study aimed to elucidate the role of methylenetetrahydrofolate reductase (MTHFR) C677T and aminoimidazole carboxami...

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Detalles Bibliográficos
Autores principales: Lima, Aurea, Monteiro, Joaquim, Bernardes, Miguel, Sousa, Hugo, Azevedo, Rita, Seabra, Vitor, Medeiros, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055378/
https://www.ncbi.nlm.nih.gov/pubmed/24967362
http://dx.doi.org/10.1155/2014/368681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055378/
https://www.ncbi.nlm.nih.gov/pubmed/24967362
http://dx.doi.org/10.1155/2014/368681

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