Cargando…

Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity

BACKGROUND: Targeting cell metabolism offers promising opportunities for the development of drugs to treat cancer. We previously found that the fatty acyl-CoA synthetase VL3 (ACSVL3) is elevated in malignant brain tumor tissues and involved in tumorigenesis. This study investigates the role of ACSVL...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Peng, Xia, Shuli, Lal, Bachchu, Shi, Xiaohai, Yang, Kil Sung, Watkins, Paul A, Laterra, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055398/
https://www.ncbi.nlm.nih.gov/pubmed/24893952
http://dx.doi.org/10.1186/1471-2407-14-401