Cargando…
Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity
BACKGROUND: Targeting cell metabolism offers promising opportunities for the development of drugs to treat cancer. We previously found that the fatty acyl-CoA synthetase VL3 (ACSVL3) is elevated in malignant brain tumor tissues and involved in tumorigenesis. This study investigates the role of ACSVL...
Autores principales: | Sun, Peng, Xia, Shuli, Lal, Bachchu, Shi, Xiaohai, Yang, Kil Sung, Watkins, Paul A, Laterra, John |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055398/ https://www.ncbi.nlm.nih.gov/pubmed/24893952 http://dx.doi.org/10.1186/1471-2407-14-401 |
Ejemplares similares
-
Depleting glioblastoma cells of very long-chain acyl-CoA synthetase 3 (ACSVL3) produces metabolic alterations in non-lipid pathways
por: Kolar, Elizabeth A., et al.
Publicado: (2023) -
VERY LONG-CHAIN ACYL-CoA SYNTHETASE-3 (ACSVL3) PROMOTES THE MALIGNANT GROWTH BEHAVIOR OF U87 GLIOMA CELLS VIA CHANGES IN CELL CYCLE WITHOUT AFFECTING APOPTOSIS
por: Yang, Haiyan, et al.
Publicado: (2023) -
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase
por: Wang, Shervin D., et al.
Publicado: (2012) -
Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration
por: Oyinlade, Olutobi, et al.
Publicado: (2018) -
Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth
por: Zhan, Daqian, et al.
Publicado: (2021)