Computational Design of Apolipoprotein E4 Inhibitors for Alzheimer's Disease Therapy from Traditional Chinese Medicine

Apolipoprotein E4 (Apo E4) is the major genetic risk factor in the causation of Alzheimer's disease (AD). In this study we utilize virtual screening of the world's largest traditional Chinese medicine (TCM) database and investigate potential compounds for the inhibition of ApoE4. We presen...

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Detalles Bibliográficos
Autores principales: Huang, Hung-Jin, Chen, Hsin-Yi, Lee, Cheng-Chun, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055423/
https://www.ncbi.nlm.nih.gov/pubmed/24967370
http://dx.doi.org/10.1155/2014/452625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055423/
https://www.ncbi.nlm.nih.gov/pubmed/24967370
http://dx.doi.org/10.1155/2014/452625

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