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Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation

Acetaminophen (APAP), is a safe analgesic and antipyretic drug at therapeutic dose, and is widely used in the clinic. However, high doses of APAP can induce hepatotoxicity and nephrotoxicity. Most studies have focused on high-dose APAP-induced acute liver and kidney injury. So far, few studies have...

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Detalles Bibliográficos
Autores principales: YU, YUNG-LUEN, YIANG, GIOU-TENG, CHOU, PEI-LUN, TSENG, HSU-HUNG, WU, TSAI-KUN, HUNG, YU-TING, LIN, PEI-SHIUAN, LIN, SHU-YU, LIU, HSIAO-CHUN, CHANG, WEI-JUNG, WEI, CHYOU-WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055434/
https://www.ncbi.nlm.nih.gov/pubmed/24682227
http://dx.doi.org/10.3892/mmr.2014.2085