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Establishment of Highly Tumorigenic Human Colorectal Cancer Cell Line (CR4) with Properties of Putative Cancer Stem Cells

BACKGROUND: Colorectal cancer (CRC) has the third highest mortality rates among the US population. According to the most recent concept of carcinogenesis, human tumors are organized hierarchically, and the top of it is occupied by malignant stem cells (cancer stem cells, CSCs, or cancer-initiating c...

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Detalles Bibliográficos
Autores principales: Rowehl, Rebecca A., Burke, Stephanie, Bialkowska, Agnieszka B., Pettet, Donald W., Rowehl, Leahana, Li, Ellen, Antoniou, Eric, Zhang, Yuanhao, Bergamaschi, Roberto, Shroyer, Kenneth R., Ojima, Iwao, Botchkina, Galina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055451/
https://www.ncbi.nlm.nih.gov/pubmed/24921652
http://dx.doi.org/10.1371/journal.pone.0099091