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Imatinib Treatment Causes Substantial Transcriptional Changes in Adult Schistosoma mansoni In Vitro Exhibiting Pleiotropic Effects

BACKGROUND: Schistosome parasites cause schistosomiasis, one of the most important infectious diseases worldwide. For decades Praziquantel (PZQ) is the only drug widely used for controlling schistosomiasis. The absence of a vaccine and fear of PZQ resistance have motivated the search for alternative...

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Detalles Bibliográficos
Autores principales: Buro, Christin, Beckmann, Svenja, Oliveira, Katia C., Dissous, Colette, Cailliau, Katia, Marhöfer, Richard J., Selzer, Paul M., Verjovski-Almeida, Sergio, Grevelding, Christoph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055459/
https://www.ncbi.nlm.nih.gov/pubmed/24921634
http://dx.doi.org/10.1371/journal.pntd.0002923