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Three-Dimensional In Vitro Models of Granuloma to Study Bacteria-Host Interactions, Drug-Susceptibility, and Resuscitation of Dormant Mycobacteria

Mycobacterium tuberculosis, Mycobacterium leprae, Mycobacterium bovis, and Mycobacterium avium subsp. paratuberculosis can survive within host macrophages in a dormant state, encased within an organized aggregate of immune host cells called granuloma. Granulomas consist of uninfected macrophages, fo...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Liam E., Abendaño, Naiara, Juste, Ramon A., Alonso-Hearn, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055484/
https://www.ncbi.nlm.nih.gov/pubmed/24967387
http://dx.doi.org/10.1155/2014/623856