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Pharmacokinetics of Anti-HBV Polyoxometalate in Rats

Polyoxometalates are non-nucleoside analogs that have been proven to exhibit broad-spectrum antiviral activity. In particular, Cs(2)K(4)Na[SiW(9)Nb(3)O(40)].H(2)O 1 shows low toxicity and high activity against HBV. The preclinical pharmacokinetics of Compound 1 in rats were characterized by establis...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Qu, Xiaofeng, Qi, Yanfei, Li, Jinhua, Song, Xiuling, Li, Li, Yin, Dehui, Xu, Kun, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055585/
https://www.ncbi.nlm.nih.gov/pubmed/24921932
http://dx.doi.org/10.1371/journal.pone.0098292