Cargando…

Pharmacokinetics of Anti-HBV Polyoxometalate in Rats

Polyoxometalates are non-nucleoside analogs that have been proven to exhibit broad-spectrum antiviral activity. In particular, Cs(2)K(4)Na[SiW(9)Nb(3)O(40)].H(2)O 1 shows low toxicity and high activity against HBV. The preclinical pharmacokinetics of Compound 1 in rats were characterized by establis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Juan, Qu, Xiaofeng, Qi, Yanfei, Li, Jinhua, Song, Xiuling, Li, Li, Yin, Dehui, Xu, Kun, Li, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055585/ https://www.ncbi.nlm.nih.gov/pubmed/24921932 http://dx.doi.org/10.1371/journal.pone.0098292

Ejemplares similares

Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats
por: Qu, Xiaofeng, et al.
Publicado: (2017)

A novel multi-epitope recombined protein for diagnosis of human brucellosis
por: Yin, Dehui, et al.
Publicado: (2016)

Synthesis, cytotoxicity and antitumour mechanism investigations of polyoxometalate doped silica nanospheres on breast cancer MCF-7 cells
por: Cao, Hongqian, et al.
Publicado: (2017)

The Intrinsic Enzyme Activities of the Classic Polyoxometalates
por: Zhang, Boyu, et al.
Publicado: (2019)

A polymeric co-assembly of subunit vaccine with polyoxometalates induces enhanced immune responses
por: Li, Xinpei, et al.
Publicado: (2021)

A Rapid Detection Method of Brucella with Quantum Dots and Magnetic Beads Conjugated with Different Polyclonal Antibodies
por: Song, Dandan, et al.
Publicado: (2017)

Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
por: Gu, Jingmin, et al.
Publicado: (2018)

Anti-RNA virus activity of polyoxometalates
por: Shigeta, Shiro, et al.
Publicado: (2006)

Promising application of polyoxometalates in the treatment of cancer, infectious diseases and Alzheimer’s disease
por: Wang, Xuechen, et al.
Publicado: (2022)

Immobilization of Polyoxometalates on Tailored Polymeric Surfaces
por: Aguado-Ureta, Saioa, et al.
Publicado: (2018)

Data on spectra of lanthanide-containing polyoxometalate
por: Li, Chunxiang, et al.
Publicado: (2020)

Anti-HBV Activities of Polysaccharides from Thais clavigera (Küster) by In Vitro and In Vivo Study
por: Tang, Fei, et al.
Publicado: (2021)

Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
por: Jia, Hongli, et al.
Publicado: (2017)

Surfactant encapsulated palladium-polyoxometalates: controlled assembly and their application as single-atom catalysts
por: He, Peilei, et al.
Publicado: (2016)

Polyoxometalate-based Supramolecular Gel
por: He, Peilei, et al.
Publicado: (2013)

A monolayer crystalline covalent network of polyoxometalate clusters
por: Li, Haoyang, et al.
Publicado: (2023)

Advances in Polyoxometalates as Electron Mediators for Photocatalytic Dye Degradation
por: Li, Ruyue, et al.
Publicado: (2023)

Ultrafiltration separation of Am(VI)-polyoxometalate from lanthanides
por: Zhang, Hailong, et al.
Publicado: (2023)

Polyoxometalate-based nanocomposites for antitumor and antibacterial applications
por: Chang, Dening, et al.
Publicado: (2022)

Recent Advances in Application of Polyoxometalates in Lignocellulose Pretreatment and Transformation
por: Deng, Haoyu, et al.
Publicado: (2023)

Ionic Self-Assembled Luminescent Nanospheres from Cationic Polyelectrolyte and Eu-Containing Polyoxometalate
por: Qiu, Juan, et al.
Publicado: (2020)

Polyoxometalate-based assemblies and functional materials
por: Song, Yu-Fei
Publicado: (2018)

Increased in vitro Anti‐HIV Activity of Caffeinium‐Functionalized Polyoxometalates
por: Enderle, Ana G., et al.
Publicado: (2021)

Oxidative Depolymerization of Cellulolytic Enzyme Lignin over Silicotungvanadium Polyoxometalates
por: Xu, Wenbiao, et al.
Publicado: (2019)

Achieving deep desulfurization with inverse-micellar polyoxometalates and oxygen
por: Wu, Jinghui, et al.
Publicado: (2021)

Antiviral Activity and Pharmacokinetics of the Hepatitis B Virus (HBV) Capsid Assembly Modulator GLS4 in Patients With Chronic HBV Infection
por: Zhang, Hong, et al.
Publicado: (2020)

Towards Covalent Photosensitizer-Polyoxometalate Dyads-Bipyridyl-Functionalized Polyoxometalates and Their Transition Metal Complexes
por: Winter, Andreas, et al.
Publicado: (2019)

Degradation and Detection of Endocrine Disruptors by Laccase-Mimetic Polyoxometalates
por: Chen, Kun, et al.
Publicado: (2022)

Preparation and Characterization of Biodegradable κ-Carrageenan Based Anti-Bacterial Film Functionalized with Wells-Dawson Polyoxometalate
por: Zhou, Feng, et al.
Publicado: (2022)

Anti-influenza Activity of a Novel Polyoxometalate Derivative (POM-4960)
por: Hosseini, Seyed Masoud, et al.
Publicado: (2012)

Polyoxometalates as components of supramolecular assemblies
por: Stuckart, Maria, et al.
Publicado: (2019)

Polyoxometalates Impact as Anticancer Agents
por: Carvalho, Fátima, et al.
Publicado: (2023)

Effect of hepatitis B virus DNA replication level and anti-HBV therapy on microvascular invasion of hepatocellular carcinoma
por: Qu, Chao, et al.
Publicado: (2019)

Adoptive immune transfer from donors offers Anti-HBV protection to HBsAb-negative patients after Allo-HSCT
por: Ren, Jinhua, et al.
Publicado: (2023)

The missing link between zeolites and polyoxometalates
por: Wang, Guangmei, et al.
Publicado: (2022)

Editorial: Emerging polyoxometalates with biological, biomedical, and health applications
por: Aureliano, Manuel, et al.
Publicado: (2022)

A Polyoxometalate-Encapsulated Metal–Organic Framework Nanoplatform for Synergistic Photothermal–Chemotherapy and Anti-Inflammation of Ovarian Cancer
por: Wang, Diqing, et al.
Publicado: (2022)

An integrated giant polyoxometalate complex for photothermally enhanced catalytic oxidation
por: Chen, Xiaofei, et al.
Publicado: (2021)

Fluorometric enhancement of the detection of H(2)O(2) using different organic substrates and a peroxidase-mimicking polyoxometalate
por: Tian, Rui, et al.
Publicado: (2019)

Polyoxometalate-based microcrystal arrays patterned on air-grid superwettable surface
por: Zhang, Tianzhan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qtid65tsmv9n2f0qmdf0e3o3ov