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Sialidase NEU3 Dynamically Associates to Different Membrane Domains Specifically Modifying Their Ganglioside Pattern and Triggering Akt Phosphorylation

Lipid rafts are known to regulate several membrane functions such as signaling, trafficking and cellular adhesion. The local enrichment in sphingolipids and cholesterol together with the low protein content allows their separation by density gradient flotation after extraction with non-ionic deterge...

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Detalles Bibliográficos
Autores principales: Bonardi, Dario, Papini, Nadia, Pasini, Mario, Dileo, Loredana, Orizio, Flavia, Monti, Eugenio, Caimi, Luigi, Venerando, Bruno, Bresciani, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055604/
https://www.ncbi.nlm.nih.gov/pubmed/24925219
http://dx.doi.org/10.1371/journal.pone.0099405